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Temporospatial inhibition of Erk signaling is required for lymphatic valve formation

Intraluminal lymphatic valves (LVs) and lymphovenous valves (LVVs) are critical to ensure the unidirectional flow of lymphatic fluid. Morphological abnormalities in these valves always cause lymph or blood reflux, and result in lymphedema. However, the underlying molecular mechanism of valve develop...

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Detalles Bibliográficos
Autores principales: Meng, Yaping, Lv, Tong, Zhang, Junfeng, Shen, Weimin, Li, Lifang, Li, Yaqi, Liu, Xin, Lei, Xing, Lin, Xuguang, Xu, Hanfang, Meng, Anming, Jia, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493226/
https://www.ncbi.nlm.nih.gov/pubmed/37691058
http://dx.doi.org/10.1038/s41392-023-01571-9