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Interleukin-6-controlled, mesenchymal stem cell-based sodium/iodide symporter gene therapy improves survival of glioblastoma-bearing mice

New treatment strategies are urgently needed for glioblastoma (GBM)—a tumor resistant to standard-of-care treatment with a high risk of recurrence and extremely poor prognosis. Based on their intrinsic tumor tropism, adoptively applied mesenchymal stem cells (MSCs) can be harnessed to deliver the th...

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Detalles Bibliográficos
Autores principales: Kitzberger, Carolin, Shehzad, Khuram, Morath, Volker, Spellerberg, Rebekka, Ranke, Julius, Steiger, Katja, Kälin, Roland E., Multhoff, Gabriele, Eiber, Matthias, Schilling, Franz, Glass, Rainer, Weber, Wolfgang A., Wagner, Ernst, Nelson, Peter J., Spitzweg, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493263/
https://www.ncbi.nlm.nih.gov/pubmed/37701849
http://dx.doi.org/10.1016/j.omto.2023.08.004