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C-terminal sequence stability profiling in Saccharomyces cerevisiae reveals protective protein quality control pathways

Protein quality control (PQC) mechanisms are essential for degradation of misfolded or dysfunctional proteins. An essential part of protein homeostasis is recognition of defective proteins by PQC components and their elimination by the ubiquitin–proteasome system, often concentrating on protein term...

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Detalles Bibliográficos
Autores principales: Hasenjäger, Sophia, Bologna, Andrea, Essen, Lars-Oliver, Spadaccini, Roberta, Taxis, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493509/
https://www.ncbi.nlm.nih.gov/pubmed/37595870
http://dx.doi.org/10.1016/j.jbc.2023.105166