Cargando…

Actionable loss of SLF2 drives B‐cell lymphomagenesis and impairs the DNA damage response

The DNA damage response (DDR) acts as a barrier to malignant transformation and is often impaired during tumorigenesis. Exploiting the impaired DDR can be a promising therapeutic strategy; however, the mechanisms of inactivation and corresponding biomarkers are incompletely understood. Starting from...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Le, Wirth, Matthias, Patra, Upayan, Stroh, Jacob, Isaakidis, Konstandina, Rieger, Leonie, Kossatz, Susanne, Milanovic, Maja, Zang, Chuanbing, Demel, Uta, Keiten‐Schmitz, Jan, Wagner, Kristina, Steiger, Katja, Rad, Roland, Bassermann, Florian, Müller, Stefan, Keller, Ulrich, Schick, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493575/
https://www.ncbi.nlm.nih.gov/pubmed/37485814
http://dx.doi.org/10.15252/emmm.202216431