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Protocol for in vivo and in vitro activation of NLRP3 inflammasome in mice using monosodium urate
Although intraperitoneal injection of monosodium urate (MSU) is an effective model for studying peritonitis, its establishment remains challenging. Here, we present a protocol for using MSU to activate the NLRP3 inflammasome in bone-marrow-derived macrophages (BMDMs) and to induce peritonitis in mic...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493585/ https://www.ncbi.nlm.nih.gov/pubmed/37682717 http://dx.doi.org/10.1016/j.xpro.2023.102554 |