Adverse bioenergetic effects of N-acyl amino acids in human adipocytes overshadow beneficial mitochondrial uncoupling

OBJECTIVE: Enhancing energy turnover via uncoupled mitochondrial respiration in adipose tissue has great potential to improve human obesity and other metabolic complications. However, the amount of human brown adipose tissue and its uncoupling protein 1 (UCP1) is low in obese patients. Recently, a c...

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Detalles Bibliográficos
Autores principales: Herrnhold, Marie, Hamp, Isabel, Plettenburg, Oliver, Jastroch, Martin, Keuper, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493596/
https://www.ncbi.nlm.nih.gov/pubmed/37683300
http://dx.doi.org/10.1016/j.redox.2023.102874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493596/
https://www.ncbi.nlm.nih.gov/pubmed/37683300
http://dx.doi.org/10.1016/j.redox.2023.102874

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