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Adverse bioenergetic effects of N-acyl amino acids in human adipocytes overshadow beneficial mitochondrial uncoupling
OBJECTIVE: Enhancing energy turnover via uncoupled mitochondrial respiration in adipose tissue has great potential to improve human obesity and other metabolic complications. However, the amount of human brown adipose tissue and its uncoupling protein 1 (UCP1) is low in obese patients. Recently, a c...
Autores principales: | Herrnhold, Marie, Hamp, Isabel, Plettenburg, Oliver, Jastroch, Martin, Keuper, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493596/ https://www.ncbi.nlm.nih.gov/pubmed/37683300 http://dx.doi.org/10.1016/j.redox.2023.102874 |
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