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Megf10‐related engulfment of excitatory postsynapses by astrocytes following severe brain injury

AIMS: To investigate astrocyte‐related phagocytosis of synapses in the ipsilateral hippocampus after traumatic brain injury (TBI). METHODS: We performed controlled cortical impact to simulate TBI in mice. Seven days postinjury, we performed cognitive tests, synapse quantification, and examination of...

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Detalles Bibliográficos
Autores principales: Zhuang, Yuan, Xu, Xiaojian, Li, Hao, Niu, Fei, Yang, Mengshi, Ge, Qianqian, Lu, Shenghua, Deng, Yu, Wu, Hongbin, Zhang, Bin, Liu, Baiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493650/
https://www.ncbi.nlm.nih.gov/pubmed/37081759
http://dx.doi.org/10.1111/cns.14223