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Amphiregulin blockade decreases the levodopa‐induced dyskinesia in a 6‐hydroxydopamine Parkinson's disease mouse model

BACKGROUND: Levodopa (L‐DOPA) is considered the most reliable drug for treating Parkinson's disease (PD) clinical symptoms. Regrettably, long‐term L‐DOPA therapy results in the emergence of drug‐induced abnormal involuntary movements (AIMs) in most PD patients. The mechanisms underlying motor f...

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Detalles Bibliográficos
Autores principales: Kambey, Piniel Alphayo, Liu, Wen Ya, Wu, Jiao, Tang, Chuanxi, Buberwa, Wokuheleza, Saro, Adonira, Nyalali, Alphonce M. K., Gao, Dianshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493657/
https://www.ncbi.nlm.nih.gov/pubmed/37101388
http://dx.doi.org/10.1111/cns.14229