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The neurotrophic activities of brain‐derived neurotrophic factor are potentiated by binding with apigenin, a common flavone in vegetables, in stimulating the receptor signaling

AIMS: We aimed to identify the neurotrophic activities of apigenin (4′,5,7‐trihydroxyflavone) via its coordination with brain‐derived neurotrophic factor (BNDF) and an elevated signaling of tyrosine kinase receptor B (Trk B receptor). METHODS: The direct binding of apigenin to BDNF was validated by...

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Detalles Bibliográficos
Autores principales: Gao, Alex Xiong, Xia, Tracy Chen‐Xi, Lin, Lish Sheng‐Ying, Dong, Tina Ting‐Xia, Tsim, Karl Wah‐Keung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493664/
https://www.ncbi.nlm.nih.gov/pubmed/37101380
http://dx.doi.org/10.1111/cns.14230