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Elamipretide reduces pyroptosis and improves functional recovery after spinal cord injury

AIMS: Elamipretide (EPT), a novel mitochondria‐targeted peptide, has been shown to be protective in a range of diseases. However, the effect of EPT in spinal cord injury (SCI) has yet to be elucidated. We aimed to investigate whether EPT would inhibit pyroptosis and protect against SCI. METHODS: Aft...

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Detalles Bibliográficos
Autores principales: Jiang, Wu, He, Fan, Ding, Guoming, Wu, Junsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10493668/
https://www.ncbi.nlm.nih.gov/pubmed/37081763
http://dx.doi.org/10.1111/cns.14221