Cargando…

Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich’s ataxia mouse model

Friedreich’s ataxia (FA) is a neurodegenerative disease resulting from a mutation in the FXN gene, leading to mitochondrial frataxin deficiency. FA patients exhibit increased visceral adiposity, inflammation, and heightened diabetes risk, negatively affecting prognosis. We investigated visceral whit...

Descripción completa

Detalles Bibliográficos
Autores principales: Turchi, Riccardo, Sciarretta, Francesca, Ceci, Veronica, Tiberi, Marta, Audano, Matteo, Pedretti, Silvia, Panebianco, Concetta, Nesci, Valentina, Pazienza, Valerio, Ferri, Alberto, Carotti, Simone, Chiurchiù, Valerio, Mitro, Nico, Lettieri-Barbato, Daniele, Aquilano, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494209/
https://www.ncbi.nlm.nih.gov/pubmed/37701569
http://dx.doi.org/10.1016/j.isci.2023.107713