The effect of forskolin and the role of Epac2A during activation, activity, and deactivation of beta cell networks

Beta cells couple stimulation by glucose with insulin secretion and impairments in this coupling play a central role in diabetes mellitus. Cyclic adenosine monophosphate (cAMP) amplifies stimulus-secretion coupling via protein kinase A and guanine nucleotide exchange protein 2 (Epac2A). With the pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Skelin Klemen, Maša, Dolenšek, Jurij, Križančić Bombek, Lidija, Pohorec, Viljem, Gosak, Marko, Slak Rupnik, Marjan, Stožer, Andraž
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494243/
https://www.ncbi.nlm.nih.gov/pubmed/37701894
http://dx.doi.org/10.3389/fendo.2023.1225486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494243/
https://www.ncbi.nlm.nih.gov/pubmed/37701894
http://dx.doi.org/10.3389/fendo.2023.1225486

Ejemplares similares