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SPI1 involvement in malignant melanoma pathogenesis by regulation of HK2 through the AKT1/mTOR pathway

Spi‐1 proto‐oncogene (SPI1) plays a vital role in carcinogenesis. Our work aimed to investigate the potential regulatory mechanism of SPI1 in melanoma. The mRNA and protein levels were measured via qRT–PCR and Western blotting. Cell viability was assessed by CCK‐8 assay. The target relationship betw...

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Detalles Bibliográficos
Autores principales: Liu, Chunlei, Qiu, Xiujuan, Gao, Jun, Gong, Zhifan, Zhou, Xiaogang, Luo, Haichao, Geng, Xuerui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494286/
https://www.ncbi.nlm.nih.gov/pubmed/37539493
http://dx.doi.org/10.1111/jcmm.17844