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Hirudin inhibits glioma growth through mTOR‐regulated autophagy

Glioma is the most common primary malignant brain tumour, and survival is poor. Hirudin has anticancer pharmacological effects through suppression of glioma cell progression, but the molecular target and mechanism are poorly understood. In this study, we observed that hirudin dose‐ and time‐dependen...

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Detalles Bibliográficos
Autores principales: Ma, Ying, Wu, Senbin, Zhao, Fanyi, Li, Huifeng, Li, Qiaohong, Zhang, Jingzhi, Li, Hua, Yuan, Zhongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494300/
https://www.ncbi.nlm.nih.gov/pubmed/37539490
http://dx.doi.org/10.1111/jcmm.17851