MiR133b‐mediated inhibition of EGFR‐PTK pathway promotes rAAV2 transduction by facilitating intracellular trafficking and augmenting second‐strand synthesis

Recombinant adeno‐associated virus (rAAV) is an extremely attractive vector in the in vivo delivery of gene therapy as it is safe and its genome is simple. However, challenges including low permissiveness to specific cells and restricted tissue specificity have hindered its clinical application. Bas...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoping, Wang, Xiao, Li, Ling, Wang, Qizhao, Xu, Wentao, Wu, Wenlin, Xie, Xiaolan, Diao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494303/
https://www.ncbi.nlm.nih.gov/pubmed/37469226
http://dx.doi.org/10.1111/jcmm.17858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494303/
https://www.ncbi.nlm.nih.gov/pubmed/37469226
http://dx.doi.org/10.1111/jcmm.17858

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