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Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease

A subset of Nucleotide-binding and leucine-rich repeat-containing receptors (NLRs) function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic conditions, proper signaling by these NLRs protect against potential autoimmune responses. These...

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Detalles Bibliográficos
Autores principales: Morrison, Holly A., Trusiano, Brie, Rowe, Audrey J., Allen, Irving C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494316/
https://www.ncbi.nlm.nih.gov/pubmed/37321320
http://dx.doi.org/10.1016/j.bj.2023.100616