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Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease
A subset of Nucleotide-binding and leucine-rich repeat-containing receptors (NLRs) function to mitigate overzealous pro-inflammatory signaling produced by NF-κB activation. Under normal pathophysiologic conditions, proper signaling by these NLRs protect against potential autoimmune responses. These...
Autores principales: | Morrison, Holly A., Trusiano, Brie, Rowe, Audrey J., Allen, Irving C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chang Gung University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494316/ https://www.ncbi.nlm.nih.gov/pubmed/37321320 http://dx.doi.org/10.1016/j.bj.2023.100616 |
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