Effect of fenofibrate and selective PPARα modulator (SPPARMα), pemafibrate on KATP channel activity and insulin secretion

OBJECTIVE: Insulin secretion is regulated by ATP-sensitive potassium (K(ATP)) channels in pancreatic beta-cells. Peroxisome proliferator-activated receptors (PPAR) α ligands are clinically used to treat dyslipidemia. A PPARα ligand, fenofibrate, and PPARγ ligands troglitazone and 15-deoxy-∆(12,14)-p...

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Detalles Bibliográficos
Autores principales: Kitamura, Shigeki, Murao, Naoya, Yokota, Shoko, Shimizu, Masaru, Ono, Tomoyuki, Seino, Yusuke, Suzuki, Atsushi, Maejima, Yuko, Shimomura, Kenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494450/
https://www.ncbi.nlm.nih.gov/pubmed/37697384
http://dx.doi.org/10.1186/s13104-023-06489-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494450/
https://www.ncbi.nlm.nih.gov/pubmed/37697384
http://dx.doi.org/10.1186/s13104-023-06489-7

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