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Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance

Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based differences in cancer biology are commonly studied using a murine model with BLCA generated by N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN). While tumors in the BBN model have been profiled, these profiles provide li...

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Detalles Bibliográficos
Autores principales: Abdel-Hafiz, Hany A., Kailasam Mani, Saravana Kumar, Huang, Wesley, Gouin, Kenneth H., Chang, Yuzhou, Xiao, Tong, Ma, Qin, Li, Zihai, Knott, Simon R.V., Theodorescu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494466/
https://www.ncbi.nlm.nih.gov/pubmed/37701814
http://dx.doi.org/10.1016/j.isci.2023.107703