Quercetin ameliorates oxidative stress-induced senescence in rat nucleus pulposus-derived mesenchymal stem cells via the miR-34a-5p/SIRT1 axis

BACKGROUND: Intervertebral disc degeneration (IDD) is a main contributor to low back pain. Oxidative stress, which is highly associated with the progression of IDD, increases senescence of nucleus pulposus-derived mesenchymal stem cells (NPMSCs) and weakens the differentiation ability of NPMSCs in d...

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Detalles Bibliográficos
Autores principales: Zhao, Wen-Jie, Liu, Xin, Hu, Man, Zhang, Yu, Shi, Peng-Zhi, Wang, Jun-Wu, Lu, Xu-Hua, Cheng, Xiao-Fei, Tao, Yu-Ping, Feng, Xin-Min, Wang, Yong-Xiang, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494568/
https://www.ncbi.nlm.nih.gov/pubmed/37700818
http://dx.doi.org/10.4252/wjsc.v15.i8.842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494568/
https://www.ncbi.nlm.nih.gov/pubmed/37700818
http://dx.doi.org/10.4252/wjsc.v15.i8.842

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