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Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression

BACKGROUND: The immunosuppressive capacity of mesenchymal stem cells (MSCs) is dependent on the “license” of several proinflammatory factors to express immunosuppressive factors such as programmed cell death 1 ligand 1 (PD-L1), which determines the clinical therapeutic efficacy of MSCs for inflammat...

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Detalles Bibliográficos
Autores principales: Chen, Zhuo, Yao, Meng-Wei, Shen, Zhi-Lin, Li, Shi-Dan, Xing, Wei, Guo, Wei, Li, Zhan, Wu, Xiao-Feng, Ao, Luo-Quan, Lu, Wen-Yong, Lian, Qi-Zhou, Xu, Xiang, Ao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494569/
https://www.ncbi.nlm.nih.gov/pubmed/37700823
http://dx.doi.org/10.4252/wjsc.v15.i8.787