Cargando…

Interferon-gamma and tumor necrosis factor-alpha synergistically enhance the immunosuppressive capacity of human umbilical-cord-derived mesenchymal stem cells by increasing PD-L1 expression

BACKGROUND: The immunosuppressive capacity of mesenchymal stem cells (MSCs) is dependent on the “license” of several proinflammatory factors to express immunosuppressive factors such as programmed cell death 1 ligand 1 (PD-L1), which determines the clinical therapeutic efficacy of MSCs for inflammat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zhuo, Yao, Meng-Wei, Shen, Zhi-Lin, Li, Shi-Dan, Xing, Wei, Guo, Wei, Li, Zhan, Wu, Xiao-Feng, Ao, Luo-Quan, Lu, Wen-Yong, Lian, Qi-Zhou, Xu, Xiang, Ao, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2023
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494569/ https://www.ncbi.nlm.nih.gov/pubmed/37700823 http://dx.doi.org/10.4252/wjsc.v15.i8.787

Ejemplares similares

Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma
por: Sainz, Bruno, et al.
Publicado: (2005)

Alpha and gamma oscillation amplitudes synergistically predict the perception of forthcoming nociceptive stimuli
por: Tu, Yiheng, et al.
Publicado: (2015)

Anti-αFR CAR-engineered NK-92 Cells Display Potent Cytotoxicity Against αFR-positive Ovarian Cancer
por: Ao, Xiang, et al.
Publicado: (2019)

Hypoxia and inflammatory factor preconditioning enhances the immunosuppressive properties of human umbilical cord mesenchymal stem cells
por: Li, Hang, et al.
Publicado: (2023)

TUMOR NECROSIS FACTOR-ALPHA IN PATIENTS WITH ALOPECIA AREATA
por: Kasumagic-Halilovic, Emina, et al.
Publicado: (2011)

Cross talk between glucose metabolism and immunosuppression in IFN-γ–primed mesenchymal stem cells
por: Yao, Mengwei, et al.
Publicado: (2022)

Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma
por: Zhou, Jiayi, et al.
Publicado: (2021)

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction
Publicado: (1994)

Toll-like Receptor agonists and alpha-galactosylceramide synergistically enhance the production of interferon-gamma in murine splenocytes
por: Ando, Tatsuya, et al.
Publicado: (2013)

Profiles of interferon-gamma and interleukin-2 in patients after allogeneic hematopoietic stem cell transplantation
por: Rybicka-Ramos, Malwina, et al.
Publicado: (2022)

Up-Regulated Expression of Interferon-Gamma, Interleukin-6 and Tumor Necrosis Factor-Alpha in the Endolymphatic Sac of Meniere's Disease Suggesting the Local Inflammatory Response Underlies the Mechanism of This Disease
por: Huang, Chao, et al.
Publicado: (2022)

Tumor necrosis factor alpha is a potent synergistic factor for the proliferation of primitive human hematopoietic progenitor cells and induces resistance to transforming growth factor beta but not to interferon gamma
Publicado: (1996)

Altered pattern of tumor necrosis factor-alpha production in peripheral blood monocytes from Crohn's disease
por: Loganes, Claudia, et al.
Publicado: (2016)

Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer
por: Quan, Yibo, et al.
Publicado: (2023)

Amauroderma rugosum Extract Suppresses Inflammatory Responses in Tumor Necrosis Factor Alpha/Interferon Gamma-Induced HaCaT Keratinocytes
por: Shiu, Polly Ho-Ting, et al.
Publicado: (2022)

3008 Role of Interferon-gamma in Natural Clearance of Chlamydia trachomatis Infection in Women
por: Jordan, Stephen, et al.
Publicado: (2019)

Genetic characteristics involving the PD-1/PD-L1/L2 and CD73/A2aR axes and the immunosuppressive microenvironment in DLBCL
por: Zhang, Tingting, et al.
Publicado: (2022)

Peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha protects a fibrotic liver from partial hepatectomy‐induced advanced liver injury through regulating cell cycle arrest
por: Zhang, Linzhong, et al.
Publicado: (2021)

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha
Publicado: (1995)

Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin
por: Langan, Ewan A., et al.
Publicado: (2013)

The Cooling Effect on Proinflammatory Cytokines Interferon-Gamma, Tumor Necrosis Factor-Alpha, and Nitric Oxide in Patients with Multiple Sclerosis
por: Poyraz, Turan, et al.
Publicado: (2013)

Genetic Polymorphism of Tumor Necrosis Factor-Alpha, Interferon-Gamma and Interleukin-10 and Association With Risk of Mycobacterium Tuberculosis Infection
por: Adane, Gashaw, et al.
Publicado: (2021)

Superinduction of immunosuppressive glioblastoma extracellular vesicles by IFN-γ through PD-L1 and IDO1
por: Jung, Mi-Yeon, et al.
Publicado: (2022)

A study of the transformation of umbilical cord mesenchymal stem cells by interferon-gamma
por: Belemezova, Kalina, et al.
Publicado: (2021)

Regulation of cytokine production by soluble CD23: costimulation of interferon gamma secretion and triggering of tumor necrosis factor alpha release
Publicado: (1994)

METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N(6)-methyladenosine modification of PD-L1 mRNA in breast cancer
por: Wan, Weijun, et al.
Publicado: (2022)

TIGIT Can Exert Immunosuppressive Effects on CD8(+) T Cells by the CD155/TIGIT Signaling Pathway for Hepatocellular Carcinoma In Vitro
por: Zhang, Changkun, et al.
Publicado: (2020)

The Gene Polymorphisms (-308G/A) and the Tumor Necrosis Factor-alpha Levels in Type 2 Diabetic Patients with and Without Tuberculosis Infection
por: Daulay, Milahayati, et al.
Publicado: (2019)

Dissecting molecular mechanisms underlying ferroptosis in human umbilical cord mesenchymal stem cells: Role of cystathionine γ-lyase/hydrogen sulfide pathway
por: Hu, Bin, et al.
Publicado: (2023)

Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells
Publicado: (1993)

Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice
por: Bluemel, Sena, et al.
Publicado: (2020)

MicroRNA-101 inhibits growth and metastasis of human ovarian cancer cells by targeting PI3K/AKT
por: Wei, Min, et al.
Publicado: (2019)

C1q(+) tumor-associated macrophages contribute to immunosuppression through fatty acid metabolic reprogramming in malignant pleural effusion
por: Zhang, Siyu, et al.
Publicado: (2023)

Laparoscopic umbilical trocar port site endometriosis: A case report
por: Ao, Xue, et al.
Publicado: (2020)

Multicentric experience with interferon gamma therapy in sepsis induced immunosuppression. A case series
por: Payen, Didier, et al.
Publicado: (2019)

LOW DOSE OF ESMOLOL ATTENUATES SEPSIS-INDUCED IMMUNOSUPPRESSION VIA MODULATING T-LYMPHOCYTE APOPTOSIS AND DIFFERENTIATION
por: Ma, Ying, et al.
Publicado: (2023)

Fibroblast-like cells Promote Wound Healing via PD-L1-mediated Inflammation Resolution
por: Wang, Xiao-hui, et al.
Publicado: (2022)

IL-6 regulates CCR5 expression and immunosuppressive capacity of MDSC in murine melanoma
por: Weber, Rebekka, et al.
Publicado: (2020)

Interferon-γ priming enhances the therapeutic effects of menstrual blood-derived stromal cells in a mouse liver ischemia-reperfusion model
por: Zhang, Qi, et al.
Publicado: (2023)

Total polysaccharides of the Sijunzi decoction attenuate tumor necrosis factor-α-induced damage to the barrier function of a Caco-2 cell monolayer via the nuclear factor-κB-myosin light chain kinase-myosin light chain pathway
por: Lu, Yue, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s8su55560onm10ct6bgte9lucs