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Different oncological features of colorectal cancer codon-specific KRAS mutations: Not codon 13 but codon 12 have prognostic value

BACKGROUND: Approximately 40% of colorectal cancer (CRC) cases are linked to Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations. KRAS mutations are associated with poor CRC prognosis, especially KRAS codon 12 mutation, which is associated with metastasis and poorer survival. However, the cl...

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Detalles Bibliográficos
Autores principales: Ahn, Hong-Min, Kim, Duck-Woo, Oh, Hyeon Jeong, Kim, Hyung Kyung, Lee, Hye Seung, Lee, Tae Gyun, Shin, Hye-Rim, Yang, In Jun, Lee, Jeehye, Suh, Jung Wook, Oh, Heung-Kwon, Kang, Sung-Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494767/
https://www.ncbi.nlm.nih.gov/pubmed/37701134
http://dx.doi.org/10.3748/wjg.v29.i32.4883