Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis

Diabetic cardiomyopathy (DCM) is a serious complication and death cause of diabetes mellitus (DM). Recent cardiology studies suggest that spermidine (SPD) has cardioprotective effects. Here, we verified the hypothesis of SPD’s protective effects on DCM. Therefore, db/db mice and primary neonatal mou...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Xu, Jiyu, Liu, Yong, Lin, Yitong, Wang, Fengge, Han, Yue, Zhang, Shumin, Gao, Xiaoyan, Xu, Changqing, Yuan, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494846/
https://www.ncbi.nlm.nih.gov/pubmed/36946337
http://dx.doi.org/10.17305/bb.2022.8846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494846/
https://www.ncbi.nlm.nih.gov/pubmed/36946337
http://dx.doi.org/10.17305/bb.2022.8846

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