Isoliensinine Attenuates Renal Fibrosis and Inhibits TGF-β1/Smad2/3 Signaling Pathway in Spontaneously Hypertensive Rats

PURPOSE: This study aimed to investigate the molecular mechanisms of isoliensinine, a kind of bibenzyl isoquinoline alkaloid which isolated from a TCM named Lotus Plumule (Nelumbo nucifera Gaertn), in treating renal interstitial fibrosis (RIF) by using RNA sequencing, KEGG analysis and in vivo exper...

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Detalles Bibliográficos
Autores principales: Yao, Mengying, Lian, Dawei, Wu, Meizhu, Zhou, Yuting, Fang, Yi, Zhang, Siyu, Zhang, Wenqiang, Yang, Yanyan, Li, Renfeng, Chen, Hong, Chen, Youqin, Shen, Aling, Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494865/
https://www.ncbi.nlm.nih.gov/pubmed/37701045
http://dx.doi.org/10.2147/DDDT.S414179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494865/
https://www.ncbi.nlm.nih.gov/pubmed/37701045
http://dx.doi.org/10.2147/DDDT.S414179

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