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Reactive astrocytes associated with prion disease impair the blood brain barrier

BACKGROUND: Impairment of the blood-brain barrier (BBB) is considered to be a common feature among neurodegenerative diseases, including Alzheimer’s, Parkinson’s and prion diseases. In prion disease, increased BBB permeability was reported 40 years ago, yet the mechanisms behind the loss of BBB inte...

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Detalles Bibliográficos
Autores principales: Kushwaha, Rajesh, Li, Yue, Makarava, Natallia, Pandit, Narayan P., Molesworth, Kara, Birukov, Konstantin G., Baskakov, Ilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494928/
https://www.ncbi.nlm.nih.gov/pubmed/37597815
http://dx.doi.org/10.1016/j.nbd.2023.106264