KIF16B drives MT1-MMP recycling in macrophages and promotes co-invasion of cancer cells

The matrix metalloproteinase MT1-MMP is a central effector of cellular proteolysis. Accordingly, regulation of the surface-localized pool of MT1-MMP is crucial for cell migration and invasion. Here, we identify the superprocessive kinesin KIF16B as a major driver of fast recycling of MT1-MMP to the...

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Detalles Bibliográficos
Autores principales: Hey, Sven, Wiesner, Christiane, Barcelona, Bryan, Linder, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494930/
https://www.ncbi.nlm.nih.gov/pubmed/37696580
http://dx.doi.org/10.26508/lsa.202302158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494930/
https://www.ncbi.nlm.nih.gov/pubmed/37696580
http://dx.doi.org/10.26508/lsa.202302158

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