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Control of Paneth cell function by HuR regulates gut mucosal growth by altering stem cell activity

Rapid self-renewal of the intestinal epithelium requires the activity of intestinal stem cells (ISCs) that are intermingled with Paneth cells (PCs) at the crypt base. PCs provide multiple secreted and surface-bound niche signals and play an important role in the regulation of ISC proliferation. Here...

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Detalles Bibliográficos
Autores principales: Xiao, Lan, Warner, Bridgette, Mallard, Caroline G, Chung, Hee K, Shetty, Amol, Brantner, Christine A, Rao, Jaladanki N, Yochum, Gregory S, Koltun, Walter A, To, Kathleen B, Turner, Douglas J, Gorospe, Myriam, Wang, Jian-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494932/
https://www.ncbi.nlm.nih.gov/pubmed/37696579
http://dx.doi.org/10.26508/lsa.202302152