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A targeted sequencing extension for transcript genotyping in single-cell transcriptomics

As no existing methods within the single-cell RNA sequencing repertoire combine genotyping of specific genomic loci with high throughput, we evaluated a straightforward, targeted sequencing approach as an extension to high-throughput droplet-based single-cell RNA sequencing. Overlaying standard gene...

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Detalles Bibliográficos
Autores principales: Van Horebeek, Lies, David, Margaux, Dedoncker, Nina, Mallants, Klara, Bijnens, Baukje, Goris, An, Dubois, Bénédicte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494938/
https://www.ncbi.nlm.nih.gov/pubmed/37696578
http://dx.doi.org/10.26508/lsa.202301971