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Inferring the Effects of Protein Variants on Protein–Protein Interactions with Interpretable Transformer Representations

Identifying pathogenetic variants and inferring their impact on protein–protein interactions sheds light on their functional consequences on diseases. Limited by the availability of experimental data on the consequences of protein interaction, most existing methods focus on building models to predic...

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Detalles Bibliográficos
Autores principales: Liu, Zhe, Qian, Wei, Cai, Wenxiang, Song, Weichen, Wang, Weidi, Maharjan, Dhruba Tara, Cheng, Wenhong, Chen, Jue, Wang, Han, Xu, Dong, Lin, Guan Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494974/
https://www.ncbi.nlm.nih.gov/pubmed/37701056
http://dx.doi.org/10.34133/research.0219