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Inferring the Effects of Protein Variants on Protein–Protein Interactions with Interpretable Transformer Representations
Identifying pathogenetic variants and inferring their impact on protein–protein interactions sheds light on their functional consequences on diseases. Limited by the availability of experimental data on the consequences of protein interaction, most existing methods focus on building models to predic...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAAS
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494974/ https://www.ncbi.nlm.nih.gov/pubmed/37701056 http://dx.doi.org/10.34133/research.0219 |