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Fat body-specific reduction of CTPS alleviates HFD-induced obesity

Obesity induced by high-fat diet (HFD) is a multi-factorial disease including genetic, physiological, behavioral, and environmental components. Drosophila has emerged as an effective metabolic disease model. Cytidine 5'-triphosphate synthase (CTPS) is an important enzyme for the de novo synthes...

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Detalles Bibliográficos
Autores principales: Liu, Jingnan, Zhang, Yuanbing, Wang, Qiao-Qi, Zhou, Youfang, Liu, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495109/
https://www.ncbi.nlm.nih.gov/pubmed/37695169
http://dx.doi.org/10.7554/eLife.85293