Cargando…
Fat body-specific reduction of CTPS alleviates HFD-induced obesity
Obesity induced by high-fat diet (HFD) is a multi-factorial disease including genetic, physiological, behavioral, and environmental components. Drosophila has emerged as an effective metabolic disease model. Cytidine 5'-triphosphate synthase (CTPS) is an important enzyme for the de novo synthes...
Autores principales: | Liu, Jingnan, Zhang, Yuanbing, Wang, Qiao-Qi, Zhou, Youfang, Liu, Ji-Long |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495109/ https://www.ncbi.nlm.nih.gov/pubmed/37695169 http://dx.doi.org/10.7554/eLife.85293 |
Ejemplares similares
-
Combined Inactivation of CTPS1 and ATR Is Synthetically Lethal to MYC-Overexpressing Cancer Cells
por: Sun, Zhe, et al.
Publicado: (2022) -
Structural basis for isoform-specific inhibition of human CTPS1
por: Lynch, Eric M., et al.
Publicado: (2021) -
Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation
por: Minet, Norbert, et al.
Publicado: (2023) -
Interfilament interaction between IMPDH and CTPS cytoophidia
por: Chang, Chia‐Chun, et al.
Publicado: (2018) -
ASNS disruption shortens CTPS cytoophidia in Saccharomyces cerevisiae
por: Zhang, Shanshan, et al.
Publicado: (2021)