Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

Tomosyn is a large, non-canonical SNARE protein proposed to act as an inhibitor of SNARE complex formation in the exocytosis of secretory vesicles. In the brain, tomosyn inhibits the fusion of synaptic vesicles (SVs), whereas its role in the fusion of neuropeptide-containing dense core vesicles (DCV...

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Detalles Bibliográficos
Autores principales: Subkhangulova, Aygul, Gonzalez-Lozano, Miguel A, Groffen, Alexander JA, van Weering, Jan RT, Smit, August B, Toonen, Ruud F, Verhage, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495110/
https://www.ncbi.nlm.nih.gov/pubmed/37695731
http://dx.doi.org/10.7554/eLife.85561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495110/
https://www.ncbi.nlm.nih.gov/pubmed/37695731
http://dx.doi.org/10.7554/eLife.85561

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