LptD depletion disrupts morphological homeostasis and upregulates carbohydrate metabolism in Escherichia coli

In a previous in silico study, we identified an essential outer membrane protein (LptD) as an attractive target for development of novel antibiotics. Here, we characterized the effects of LptD depletion on Escherichia coli physiology and morphology. An E. coli CRISPR interference (CRISPRi) strain wa...

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Detalles Bibliográficos
Autores principales: Frisinger, Frida Svanberg, Jana, Bimal, Ortiz-Marquez, Juan C, van Opijnen, Tim, Donadio, Stefano, Guardabassi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495129/
https://www.ncbi.nlm.nih.gov/pubmed/37701421
http://dx.doi.org/10.1093/femsmc/xtad013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495129/
https://www.ncbi.nlm.nih.gov/pubmed/37701421
http://dx.doi.org/10.1093/femsmc/xtad013

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