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信使RNA药物修饰及其递送系统研究进展
Messenger RNA (mRNA) has shown tremendous potential in disease prevention and therapy. The clinical application requires mRNA with enhanced stability and high translation efficiency, ensuring it not to be degraded by nucleases and targeting to specific tissues and cells. mRNA immunogenicity can be r...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
《浙江大学学报》编辑部
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495253/ https://www.ncbi.nlm.nih.gov/pubmed/37643978 http://dx.doi.org/10.3724/zdxbyxb-2023-0101 |