RBFOX2 recognizes N(6)-methyladenosine to suppress transcription and block myeloid leukaemia differentiation

N(6)-methyladenosine (m(6)A) methylation can be deposited on chromatin-associated RNAs (caRNAs) by the RNA methyltransferase complex (MTC) to regulate chromatin state and transcription. However, the mechanism by which MTC is recruited to distinct genomic loci remains elusive. Here we identify RBFOX2...

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Detalles Bibliográficos
Autores principales: Dou, Xiaoyang, Xiao, Yu, Shen, Chao, Wang, Kitty, Wu, Tong, Liu, Chang, Li, Yini, Yu, Xianbin, Liu, Jun, Dai, Qing, Pajdzik, Kinga, Ye, Chang, Ge, Ruiqi, Gao, Boyang, Yu, Jianhua, Sun, Shuying, Chen, Mengjie, Chen, Jianjun, He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495261/
https://www.ncbi.nlm.nih.gov/pubmed/37640841
http://dx.doi.org/10.1038/s41556-023-01213-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495261/
https://www.ncbi.nlm.nih.gov/pubmed/37640841
http://dx.doi.org/10.1038/s41556-023-01213-w

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