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RBFOX2 recognizes N(6)-methyladenosine to suppress transcription and block myeloid leukaemia differentiation
N(6)-methyladenosine (m(6)A) methylation can be deposited on chromatin-associated RNAs (caRNAs) by the RNA methyltransferase complex (MTC) to regulate chromatin state and transcription. However, the mechanism by which MTC is recruited to distinct genomic loci remains elusive. Here we identify RBFOX2...
Autores principales: | Dou, Xiaoyang, Xiao, Yu, Shen, Chao, Wang, Kitty, Wu, Tong, Liu, Chang, Li, Yini, Yu, Xianbin, Liu, Jun, Dai, Qing, Pajdzik, Kinga, Ye, Chang, Ge, Ruiqi, Gao, Boyang, Yu, Jianhua, Sun, Shuying, Chen, Mengjie, Chen, Jianjun, He, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495261/ https://www.ncbi.nlm.nih.gov/pubmed/37640841 http://dx.doi.org/10.1038/s41556-023-01213-w |
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