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Lipid saturation controls nuclear envelope function

The nuclear envelope (NE) is a spherical double membrane with elastic properties. How NE shape and elasticity are regulated by lipid chemistry is unknown. Here we discover lipid acyl chain unsaturation as essential for NE and nuclear pore complex (NPC) architecture and function. Increased lipid satu...

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Detalles Bibliográficos
Autores principales: Romanauska, Anete, Köhler, Alwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495262/
https://www.ncbi.nlm.nih.gov/pubmed/37591950
http://dx.doi.org/10.1038/s41556-023-01207-8