Treatment of older adults with FLT3-mutated AML: Emerging paradigms and the role of frontline FLT3 inhibitors

FLT3 is the most frequently mutated gene in acute myeloid leukemia (AML), with FLT3 internal tandem duplication (ITD) mutations being associated with a more aggressive clinical course. While two large, randomized clinical trials have shown a survival benefit with the frontline use of an oral FLT3 in...

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Detalles Bibliográficos
Autores principales: Short, Nicholas J., Nguyen, Daniel, Ravandi, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495326/
https://www.ncbi.nlm.nih.gov/pubmed/37696819
http://dx.doi.org/10.1038/s41408-023-00911-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495326/
https://www.ncbi.nlm.nih.gov/pubmed/37696819
http://dx.doi.org/10.1038/s41408-023-00911-w

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