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Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress
The tumor suppressor p53 primarily functions as a mediator of DNA damage-induced cell death, thereby contributing to the efficacy of genotoxic anticancer therapeutics. Here, we show, on the contrary, that cancer cells can employ genotoxic stress-induced p53 to acquire treatment resistance through th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495329/ https://www.ncbi.nlm.nih.gov/pubmed/37696858 http://dx.doi.org/10.1038/s41420-023-01638-0 |