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EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer

Ferroptosis is a form of regulated cell death characterized by oxidative injury-induced lipid peroxidation. However, the detailed protein post-translational modification regulatory mechanism of ferroptosis remains largely unknown. Here, we report that E1A binding protein P300 (EP300) acetyltransfera...

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Detalles Bibliográficos
Autores principales: Wang, Yuan, Liu, Yang, Wang, Cong, Kang, Rui, Tang, Daolin, Liu, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495396/
https://www.ncbi.nlm.nih.gov/pubmed/37696842
http://dx.doi.org/10.1038/s41598-023-42136-8