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CBX4 deletion promotes tumorigenesis under Kras(G12D) background by inducing genomic instability

Chromobox protein homolog 4 (CBX4) is a component of the Polycomb group (PcG) multiprotein Polycomb repressive complexes 1 (PRC1), which is participated in several processes including growth, senescence, immunity, and tissue repair. CBX4 has been shown to have diverse, even opposite functions in dif...

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Detalles Bibliográficos
Autores principales: Chen, Fangzhen, Hou, Wulei, Yu, Xiangtian, Wu, Jing, Li, Zhengda, Xu, Jietian, Deng, Zimu, Chen, Gaobin, Liu, Bo, Yin, Xiaoxing, Yu, Wei, Zhang, Lei, Xu, Guoliang, Ji, Hongbin, Liang, Chunmin, Wang, Zuoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495400/
https://www.ncbi.nlm.nih.gov/pubmed/37696812
http://dx.doi.org/10.1038/s41392-023-01623-0