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Study of β(1)-transferrin and β(2)-transferrin using microprobe-capture in-emitter elution and high-resolution mass spectrometry

Cerebrospinal fluid (CSF) leak can be diagnosed in clinical laboratories by detecting a diagnostic marker β(2)-transferrin (β(2)-Tf) in secretion samples. β(2)-Tf and the typical transferrin (Tf) proteoform in serum, β(1)-transferrin (β(1)-Tf), are Tf glycoforms. An innovative affinity capture techn...

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Detalles Bibliográficos
Autores principales: Luo, Ruben Yiqi, Pfaffroth, Christopher, Yang, Samuel, Hoang, Kevin, Yeung, Priscilla S.-W., Zehnder, James L., Shi, Run-Zhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495423/
https://www.ncbi.nlm.nih.gov/pubmed/37696850
http://dx.doi.org/10.1038/s41598-023-42064-7