Discovery of l-threonine transaldolases for enhanced biosynthesis of beta-hydroxylated amino acids

Beta-hydroxy non-standard amino acids (β-OH-nsAAs) have utility as small molecule drugs, precursors for beta-lactone antibiotics, and building blocks for polypeptides. While the L-threonine transaldolase (TTA), ObiH, is a promising enzyme for β-OH-nsAA biosynthesis, little is known about other natur...

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Detalles Bibliográficos
Autores principales: Jones, Michaela A., Butler, Neil D., Anderson, Shelby R., Wirt, Sean A., Govil, Ishika, Lyu, Xinyi, Fang, Yinzhi, Kunjapur, Aditya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495429/
https://www.ncbi.nlm.nih.gov/pubmed/37696954
http://dx.doi.org/10.1038/s42003-023-05293-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495429/
https://www.ncbi.nlm.nih.gov/pubmed/37696954
http://dx.doi.org/10.1038/s42003-023-05293-0

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