Identifying novel mechanisms of biallelic TP53 loss refines poor outcome for patients with multiple myeloma

Biallelic TP53 inactivation is the most important high-risk factor associated with poor survival in multiple myeloma. Classical biallelic TP53 inactivation has been defined as simultaneous mutation and copy number loss in most studies; however, numerous studies have demonstrated that other factors c...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Enze, Sudha, Parvathi, Becker, Nathan, Jaouadi, Oumaima, Suvannasankha, Attaya, Lee, Kelvin, Abonour, Rafat, Abu Zaid, Mohammad, Walker, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495448/
https://www.ncbi.nlm.nih.gov/pubmed/37696786
http://dx.doi.org/10.1038/s41408-023-00919-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495448/
https://www.ncbi.nlm.nih.gov/pubmed/37696786
http://dx.doi.org/10.1038/s41408-023-00919-2

Ejemplares similares