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Identifying novel mechanisms of biallelic TP53 loss refines poor outcome for patients with multiple myeloma
Biallelic TP53 inactivation is the most important high-risk factor associated with poor survival in multiple myeloma. Classical biallelic TP53 inactivation has been defined as simultaneous mutation and copy number loss in most studies; however, numerous studies have demonstrated that other factors c...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495448/ https://www.ncbi.nlm.nih.gov/pubmed/37696786 http://dx.doi.org/10.1038/s41408-023-00919-2 |