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Identification of experimentally-supported poly(A) sites in single-cell RNA-seq data with SCINPAS

Alternative polyadenylation is a main driver of transcriptome diversity in mammals, generating transcript isoforms with different 3’ ends via cleavage and polyadenylation at distinct polyadenylation (poly(A)) sites. The regulation of cell type-specific poly(A) site choice is not completely resolved,...

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Detalles Bibliográficos
Autores principales: Moon, Youngbin, Burri, Dominik, Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495540/
https://www.ncbi.nlm.nih.gov/pubmed/37705828
http://dx.doi.org/10.1093/nargab/lqad079