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Variation of extrachromosomal circular DNA in cancer cell lines

The presence of oncogene carrying eccDNAs is strongly associated with carcinogenesis and poor patient survival. Tumour biopsies and in vitro cancer cell lines are frequently utilized as models to investigate the role of eccDNA in cancer. However, eccDNAs are often lost during the in vitro growth of...

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Detalles Bibliográficos
Autores principales: dos Santos, Carl Rung, Hansen, Lasse Bøllehuus, Rojas-Triana, Monica, Johansen, Astrid Zedlitz, Perez-Moreno, Mirna, Regenberg, Birgitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10495552/
https://www.ncbi.nlm.nih.gov/pubmed/37705597
http://dx.doi.org/10.1016/j.csbj.2023.08.027